Microvessel density is as a prognostic factor in canine cutaneous mast cell tumors

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Microvessel density is as a prognostic factor in canine cutaneous mast cell tumors

Background Mast cell tumors represent almost 25% of canine skin neoplasms. These tumors are classified in three grades of differentiation, based on histological features. However, this grading system is a method based on subjective parameters, which generate intraand interobserver variations. The microcirculation is an important feature to the primary tumor expansion, dissemination and metastas...

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Treatment of Canine Cutaneous Mast Cell Tumors Review of the Treatment of Canine Cutaneous Mast Cell Tumors

ABST RACT The most common skin tumor in dogs is the mast cell tumor, with an incidence of close to 20% in the canine population. The behavior and progression of MCT are highly heterogeneous, and range from relatively benign to extremely aggressive tumors. There are many treatment options for dogs with mast cell tumors, including surgery, radiation therapy and chemotherapy. Although surgical exc...

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Nuclear morphometry in cytopathology: a prognostic indicator for canine cutaneous mast cell tumors.

Twenty-nine canine cutaneous mast cell tumors (MCTs) were morphometrically analyzed with regard to mean nuclear area (MNA) using cytopathology smears. The results showed a correlation between MNA and survival. When graded into 2 morphometrically different groups, there were statistically significant differences among high- and low-grade MCTs, regarding both Romanowsky-type stain and hematoxylin...

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Canine Mast Cell Tumors

Initial work up of a mast cell tumor (MCT)will involve diagnosis by FNA and staging. The initial staging performed will depend on the index of suspicion that the mass is a grade II or III MCT and clinician’s preference. Cytology is generally diagnostic for MCT. However, an incisional biopsy to determine grade is recommended in some cases. The histological grade may be important to determine in ...

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Tumor microvessel density–associated mast cells in canine nodal lymphoma

OBJECTIVE Mast cells are associated in angiogenesis in various human and animal neoplasms. However, association of mast cells with tumor microvessel density in canine lymphoma was not previously documented. The objective of the study is to determine if mast cells are increased in canine nodal lymphomas and to evaluate their correlation with tumor microvessel density and grading of lymphomas. ...

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ژورنال

عنوان ژورنال: BMC Proceedings

سال: 2013

ISSN: 1753-6561

DOI: 10.1186/1753-6561-7-s2-p62